Placenta Increta: Postpartum Monitoring of Plasma Cell-free Fetal DNA
نویسندگان
چکیده
منابع مشابه
Placenta increta: Postpartum monitoring of plasma cell-free fetal DNA.
is more sensitive but requires two steps [two rounds of amplification (PCR LDR) are needed]. The costs for setup are larger (PCR primers and three labeled oligonucleotides are needed per SNP) with respect to PCR/RFLP and allele-specific PCR but are similar for the TaqMan assay. The main advantage consists in the inherent multiplexing capability that can increase throughput, which decreases cost...
متن کاملIncreased cell-free fetal DNA in plasma of two women with invasive placenta.
Invasive placenta, often involving placenta accreta, placenta increta, and placenta percreta, is a life-threatening complication of pregnancy characterized by invasion of placental villi into the underlying myometrium. Invasive placenta is usually diagnosed as a result of abnormalities encountered during removal of the placenta at delivery. Because of profuse hemorrhaging in the early postpartu...
متن کاملIntroducing a New and Simple Protocol for Capillary Electrophoresis of Cell Free Fetal Double Stranded DNA
Isolation of cell free fetal DNA (cffDNA) from maternal serum usually leads to very low concentrations of DNA impeding further resolving through conventional methods of electrophoresis. Although several protocols have been described for capillary electrophoresis (CE) of double stranded DNA, they usually need using special polymers or coated capillaries which degrade over time. Herein, we propos...
متن کاملA Case of Placenta Prævia Increta
By placenta accreta is meant an abnormal adherence of the whole, or part, of the placenta to the uterine wall due to partial or complete absence of the decidua basalis, especially the spongiosum layer. Placenta increta is an uncommon variant of this condition when, in addition, the plfacenta invades the uterine musculature. The incidence of placenta accreta varies from observer to observer, and...
متن کاملA NEW WORKFLOW OF FETAL DNA PREDICTION FROM CELL-FREE DNA IN MATERNAL PLASMA by
Prediction of fetal DNA allows diagnosing known/passed mutations before child’s birth. Public health significance of such early testing is that it can reassure parents who have negative results and offers timely information for those with abnormal results. My dissertation work presents a new approach of reconstructing fetal DNA from maternal plasma. The method works because plasma from pregnant...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2003
ISSN: 0009-9147,1530-8561
DOI: 10.1373/49.9.1540